CK-3197

• Description:

  CK-3197 is a weak inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase (CAMP PDEl) . CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure[1].

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/ck-3197.html

• Smiles:

  O=C(C1=C(CC)NC(N1C(C2=CC=CC=C2)=O)=O)C3=CC=C(N4C(C)=NCC4)C=C3

• Molecular Formula:

  C23H22N4O3

• Molecular Weight:

  402.45

• References & Citations:

  [1]Greenberg S, et al. Hemodynamic and myocardial energetic effects of CK-3197, a selective positive inotropic agent. J Cardiovasc Pharmacol. 1991 Jan;17 (1) :145-53.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  132523-92-3