CK-666

• Description :

  CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 μM) . CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  Arp2/3 Complex; HIV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Cytoskeleton

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/ck-666.html

• Purity :

  99.95

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(NCCC1=C(C)NC2=C1C=CC=C2)C3=CC=CC=C3F

• Molecular Formula :

  C18H17FN2O

• Molecular Weight :

  296.34

• Precautions :

  H302

• References & Citations :

  +

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HIV-1

• CAS Number :

  [442633-00-3]