CK-119

• Description:

  CK-119 is a potent interleukin-1 blocker. CK-119 inhibits the cell growth of fibroblast-like corneal and conjunctival cells, mainly by inhibiting DNA and RNA syntheses[1].

• UNSPSC:

  12352005

• Target:

  Interleukin Related

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ck-119.html

• Smiles:

  O=C (C1=NN (C) C (C=NN (CC2=CC=C (Cl) C=C2) C3=O) =C3C1 (C) C (OCC) =O) OCC

• Molecular Formula:

  C21H23ClN4O5

• Molecular Weight:

  446.88

• References & Citations:

  [1]Bo X, et al. Inhibition of fibroblast-like cell proliferation by interleukin-1 blockers, CK-119 and CK-122. Zhongguo Yao Li Xue Bao. 1998 Jul;19 (4) :304-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  IL-1

• CAS Number:

  197917-10-5