CK-119

• Description :

  CK-119 is a potent interleukin-1 blocker. CK-119 inhibits the cell growth of fibroblast-like corneal and conjunctival cells, mainly by inhibiting DNA and RNA syntheses[1].

• UNSPSC :

  12352005

• Target :

  Interleukin Related

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ck-119.html

• Smiles :

  O=C(C1=NN(C)C(C=NN(CC2=CC=C(Cl)C=C2)C3=O)=C3C1(C)C(OCC)=O)OCC

• Molecular Formula :

  C21H23ClN4O5

• Molecular Weight :

  446.88

• References & Citations :

  [1]Bo X, et al. Inhibition of fibroblast-like cell proliferation by interleukin-1 blockers, CK-119 and CK-122. Zhongguo Yao Li Xue Bao. 1998 Jul;19 (4) :304-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  IL-1

• CAS Number :

  [197917-10-5]