CK-119

CAT: 0804-HY-123195Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123195Size:1 Each
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Description
CK-119 is a potent interleukin-1 blocker. CK-119 inhibits the cell growth of fibroblast-like corneal and conjunctival cells, mainly by inhibiting DNA and RNA syntheses[1].
CAS Number
[197917-10-5]
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ck-119.html
Smiles
O=C(C1=NN(C)C(C=NN(CC2=CC=C(Cl)C=C2)C3=O)=C3C1(C)C(OCC)=O)OCC
Molecular Formula
C21H23ClN4O5
Molecular Weight
446.88
References & Citations
[1]Bo X, et al. Inhibition of fibroblast-like cell proliferation by interleukin-1 blockers, CK-119 and CK-122. Zhongguo Yao Li Xue Bao. 1998 Jul;19 (4) :304-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-1

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