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ER6L2 rabbit pAb

CAT: 0855-ES16702-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES16702-01Size:50 µL
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Background
This gene encodes a member of the Snf2 family of helicase-like proteins. The encoded protein may play a role in DNA repair and mitochondrial function. Mutations in this gene have been associated with bone marrow failure syndrome 2. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Apr 2014]
Description
This gene encodes a member of the Snf2 family of helicase-like proteins. The encoded protein may play a role in DNA repair and mitochondrial function. Mutations in this gene have been associated with bone marrow failure syndrome 2. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Apr 2014],
UniProt
A4D997
Swiss Prot
A4D997
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human ER6L2 AA range: 193-243
Target
ER6L2
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus, mitochondrion, microtubule organizing center

UniProtKB · Q5T890

DNA excision repair protein ERCC-6-like 2

ER6L2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5T890
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERCC6L2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.-
Processing
—
Secondary accessions
A0A590UJ07, A4D997, B2RTP8, Q49AM9, Q5T892, Q8N663, Q8N9D0, Q9NPM7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative initiationAlternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

CentromereChromosomeCytoplasmCytoskeletonMitochondrionNucleus

Biological process

DNA damageDNA repair

Molecular function

DNA-bindingHelicaseHydrolase

PTM

Phosphoprotein

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