TGP-377/421

• Description:

  TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 inhibitor that binds a functional site in both miRNAs[1].

• Product Name Alternative:

  Targapre-miR-377/421

• UNSPSC:

  12352005

• Target:

  MicroRNA

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/tgp-377-421.html

• Purity:

  98.17

• Solubility:

  DMSO : 66.67 mg/mL (ultrasonic)

• Smiles:

  NC1=CC=C2C(N=C(C3=CC=CC(C4=NC5=CC(N)=CC=C5N4)=C3)N2)=C1

• Molecular Formula:

  C20H16N6

• Molecular Weight:

  340.38

• References & Citations:

  [1]Haniff HS, et al. Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions. Nat Chem. 2020 Oct;12 (10) :952-961.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [16752-89-9]