TRPV2 rabbit pAb

• Background:

  This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul 2008],

• Synonyms:

  Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)

• Gene ID:

  51393

• UniProt:

  Q9Y5S1

• Cellular Locus:

  Cell membrane ; Multi-pass membrane protein. Cytoplasm. Melanosome. Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human TRPV2 AA range: 493-543

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IF, IP

• Validated Applications:

  WB, IF, IP

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000; IF/ICC 1:100-500; IP 1:50-200

• Molecular Weight:

  85kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  85 kD

• Subcellular Location:

  Cell membrane ; Multi-pass membrane protein . Cytoplasm . Melanosome . Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .

• Other Product Names:

  Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)

• Gene ID (Human):

  51393

• SwissProt (Human):

  Q9Y5S1