TRPV5 rabbit pAb

• Background:

  Transient receptor potential cation channel subfamily V member 5 (TRPV5) Homo sapiens This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]

• Description:

  Transient receptor potential cation channel subfamily V member 5 (TRPV5) Homo sapiens This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008],

• UniProt:

  Q9NQA5

• Swiss Prot:

  Q9NQA5

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  80kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  80kD

• Fragment:

  IgG

• Subcellular Location:

  Apical cell membrane ; Multi-pass membrane protein . Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity) . The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3 (PubMed:18768590) . .

• Gene ID (Human):

  56302