TRP2 rabbit pAb

• Background:

  Catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate., cofactor:Binds 2 zinc ions per subunit., function:Involved in regulating eumelanin and phaeomelanin levels., pathway:Pigment biosynthesis; melanin biosynthesis., similarity:Belongs to the tyrosinase family., subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.

• Description:

  Catalytic activity: L-dopachrome = 5, 6-dihydroxyindole-2-carboxylate. Cofactor: Binds 2 zinc ions per subunit. function: Involved in regulating eumelanin and phaeomelanin levels. pathway: Pigment biosynthesis; melanin biosynthesis. similarity: Belongs to the tyrosinase family. subunit: Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.

• UniProt:

  P40126

• Swiss Prot:

  P40126

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human DCT. AA range:51-100

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  60kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  60kD

• Fragment:

  IgG

• Subcellular Location:

  Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .

• Other Product Names:

  DCT; TYRP2; L-dopachrome tautomerase; DCT; DT; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2

• Gene ID (Human):

  1638