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AJ-76 (hydrochloride)

CAT: 0804-HY-101065-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101065-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AJ-76 hydrochloride ((+) -AJ 76 hydrochloride) is an antagonist of dopamine autoreceptor with pKi values of 6.95, 6.67, 6.37, 6.21 and 6.07 for hD3, hD4, hD2S, hD2L and rD2 receptors, respectively.
CAS Number
85378-82-1
Product Name Alternative
(+) -AJ 76 (hydrochloride) ; (1S,2R) -AJ 76 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/aj-76-hydrochloride.html
Purity
98.55
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C) |Methanol : 25 mg/mL (ultrasonic)
Smiles
CCCN[C@H]1[C@@H](C)C2=C(C(OC)=CC=C2)CC1.Cl
Molecular Formula
C15H24ClNO
Molecular Weight
269.82
Precautions
H302, H315, H319, H335
References & Citations
[1]Kullingsjö H, et al. Effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+) -AJ76, on locomotor activity and brain DA metabolism in the rat. Eur J Pharmacol. 1991 Dec 3;205 (3) :241-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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