PD-0299685

• Description :

  PD-0299685 is a potent Ca2+ channel α2δ ligand. PD-0299685 is promising for research of refractory genito-urinary pain and interstitial cystitis/bladder pain syndrome[1][2].

• UNSPSC :

  12352211

• Target :

  Calcium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/pd-0299685.html

• Smiles :

  CCC[C@@H](C)C[C@H](CN)CC(O)=O

• Molecular Formula :

  C10H21NO2

• Molecular Weight :

  187.28

• References & Citations :

  [1]Nickel JC, et al. Investigation of a Ca2+ channel α2δ ligand for the treatment of interstitial cystitis: results of a randomized, double-blind, placebo controlled phase II trial. J Urol. 2012 Sep;188 (3) :817-23.|[2]Nickel J C, et al. 821 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE IIA TRIAL OF A CA2+ CHANNEL α2Δ LIGAND, PD-0299685, FOR THE TREATMENT OF INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME[J]. The Journal of Urology, 2012, 187 (4S) : e335-e335.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [313651-33-1]