SHP2-IN-28
CAT:
804-HY-162476
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SHP2-IN-28
- UNSPSC Description: SHP2-IN-28 (Compound 7188-0011) is an inhibitor of SHP2 (IC50=54.31 μM). SHP2-IN-28 exerts its inhibitory effect by binding to the variable site of SHP2 with high selectivity[1].
- Target Antigen: SHP2
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/shp2-in-28.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(/C(C1=CC=CC=C1)=N/O)NCC2CCNCC2
- Molecular Weight: 261.32
- References & Citations: [1]Yuan Z et al. Discovery of a novel SHP2 allosteric inhibitor using virtual screening, FMO calculation, and molecular dynamic simulation. J Mol Model. 2024 Apr 13;30(5):131.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported