CDK2-IN-32

• Description :

  CDK2-IN-32 (Compound 5g) is a selective CDK2 inhibitor with an IC50 of 0.21 μM. CDK2-IN-32 shows cytotoxicity against Vero cells with an IC50 of 28.52 μM[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; CDK

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cdk2-in-32.html

• Smiles :

  ClC1=CC(Cl)=CC(C(CN2C=NC3=C(N=CN=C23)NCC4=CC=CO4)=O)=C1

• Molecular Formula :

  C18H13Cl2N5O2

• Molecular Weight :

  402.23

• References & Citations :

  [1]Shah A, et al. Novel purine derivatives as selective CDK2 inhibitors with potential anticancer activities: Design, synthesis and biological evaluation. Bioorg Chem. 2024 Sep 24;153:107841.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported