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BAY-204

CAT: 0804-HY-145940-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145940-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY-204 (BRD3727) is a potent, ATP-competitive, and selective CSNK1α inhibitor (IC50 = 2 nM at 10 μM ATP; 12 nM at 1 mM ATP) . BAY-204 can be used for the study of acute myeloid leukemia (AML) [1][2].
CAS Number
2468784-57-6
Product Name Alternative
BRD3727
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bay-204.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(NC(C3=CC=NC(NC([C@@H](CC(F)F)C4=CC=C(F)C=C4)=O)=C3)=C2NC5=CC=CC=C5)CCN1C
Molecular Formula
C29H26F3N5O2
Molecular Weight
533.54
References & Citations
[1]Volker Schulze, et al. 3-amino-2-[2- (acylamino) pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors. WO2020161257 A1. |[2]Steven M. Corsello, et al. Abstract 3588: Discovery of potent and selective CSNK1A1 inhibitors for solid tumor therapy.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1

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