ASK1-IN-2
CAT:
804-HY-131969-01
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ASK1-IN-2
- CAS Number: 2541792-70-3
- UNSPSC Description: ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can be used for the research of ulcerative colitis[1].
- Target Antigen: Apoptosis; MAP3K
- Type: Reference compound
- Related Pathways: Apoptosis;MAPK/ERK Pathway
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/ask1-in-2.html
- Purity: 99.55
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(C(N1)=CC2=C1C=C(F)C=C2)NC3=NC(C4=NN=CN4C(C)C)=CC=C3
- Molecular Weight: 364.38
- References & Citations: [1]Hou S, et, al. Structure-based discovery of 1H-indole-2-carboxamide derivatives as potent ASK1 inhibitors for potential treatment of ulcerative colitis. Eur J Med Chem. 2020 Dec 24;211:113114.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported