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LY 301875

CAT: 0804-HY-105440Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105440Size:1 Each
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Description
LY 301875 is a potent and orally active angiotensin II receptor type 1 (AT1) antagonist with a pKB value of 9.6[1].
CAS Number
154668-27-6
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ly-301875.html
Smiles
CCCCCC[C@@H](N1C=C(N=C1)NC(C2=C(C=CC=C2)S(=O)(O)=O)=O)C(N3[C@@H](C[C@@H](C3)OC4=CC=C(C=C4)CC(O)=O)C(O)=O)=O
Molecular Formula
C31H36N4O10S
Molecular Weight
656.70
References & Citations
[1]Boyd, D. B., et al. Molecular Modeling and Quantitative Structure—Activity Relationship Studies in Pursuit of Highly Potent Substituted Octanoamide Angiotensin II Receptor Antagonists. Computer-Aided Molecular Design, 1995, 14-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AT1 Receptor

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