AK-4

• Description :

  AK-4 is a glucose-lowering agent, acting function as a mitochondrial uncoupler[1].

• UNSPSC :

  12352005

• Target :

  Mitochondrial Metabolism

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ak-4.html

• Smiles :

  ClC(C=C(Cl)C=C1)=C1CN2C3=CC=CC=C3C(/C=C4SC(N(CC(O)=O)C\4=O)=O)=C2

• Molecular Formula :

  C21H14Cl2N2O4S

• Molecular Weight :

  461.32

• References & Citations :

  [1]Kousaxidis A, et al. Rational design and synthesis of novel N-benzylindole-based epalrestat analogs as selective aldose reductase inhibitors: An unexpected discovery of a new glucose-lowering agent (AK-4) acting as a mitochondrial uncoupler. Eur J Med Chem. 2025 Jan 5;281:117035.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported