AK-IN-1

CAT: 0804-HY-148327-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-148327-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AK-IN-1 (compound 4072-2732) is an adenosine kinase (AK) inhibitor that is competitive for adenosine (Ado) but not for ATP. AK-IN-1 inhibits 86%, 87% and 89% of AK activity at concentrations of 2, 4 and 10 µM, respectively. AK-IN-1 has good potential for research in many disease areas, including ischaemia, inflammation and seizures[1].
CAS Number
[378775-98-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Adenosine Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ak-in-1.html
Purity
99.21
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCNC1=NC=NC2=C1C(C3=CC=C(OC)C=C3)=C(C4=CC=C(C=C4)OC)O2
Molecular Formula
C22H21N3O4
Molecular Weight
391.42
Precautions
H302, H315, H319
References & Citations
[1]Park J, et al. Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase. Protein J. 2007 Apr;26 (3) :203-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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