α-CGRP (mouse, rat) (TFA)

CAT: 0804-HY-P0203A-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P0203A-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
α-CGRP (mouse, rat) TFA, a neuropeptide (calcitonin gene-related peptide (CGRP) ) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) TFA can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) TFA has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies[1][2][3][4].
Product Name Alternative
CGRP (83-119), mouse, rat (TFA)
UNSPSC
12352209
Target
CGRP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/α-cgrp-mouse-rat-tfa.html
Purity
99.82
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CSSC[C@@H](C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@H]5[C@H](O)C)=O)=O)=O)=O)[C@H](CO)N.OC(C(F)(F)F)=O
Molecular Formula
C162H262N50O52S2.C2HF3O2
Molecular Weight
3920.27
References & Citations
[1]Whitby K, et al. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. J Virol. 2005 Jul;79 (14) :8698-706.|[2]Xu H, et al. Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. Immunity. 2019 Oct 15;51 (4) :696-708.e9.|[3]Arulmani U, et al. Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats. Basic Clin Pharmacol Toxicol. 2004 Jun;94 (6) :291-7.|[4]Park SH, et al. Role of α-CGRP in the regulation of neurotoxic responses induced by kainic acid in mice. Peptides. 2013 Jun;44:158-62.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Citation 01
Adv Sci (Weinh) . 2025 Apr;12 (14) :e2409251.|Br J Pharmacol. 2024 May 7.|Cell Mol Life Sci. 2024 Aug 28;81 (1) :373.|Mater Today Bio. 2025 Aug 14:34:102181.|Sci Adv. 2025 Aug 15;11 (33) :eadx9221.

Related Products

CatalogName
HY-P1548A-01β-CGRP, human (TFA)
HY-P1071A-01α-CGRP (human) (TFA)
HY-P4946A-01Biotinyl-α-CGRP (human) (TFA)
HY-P2601ATyr-α-CGRP (human) (TFA)
HY-P0203-01α-CGRP (mouse, rat)
HY-P1462ACalcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA)
HY-P4941-01Biotinyl-α-CGRP (mouse, rat)
HY-P0203Bβ-CGRP (mouse)
HY-P5077A-01Guanylin (mouse, rat) (TFA)
HY-P0209-01Rat CGRP- (8-37)

Alternative Products

CatalogName
MF-0156728-01α-CGRP (mouse, rat) TFA
B5061-.5CGRP (rat) TFA
MF-0155476-01α-CGRP, rat TFA
MBS5820206alpha-CGRP (mouse, rat) TFA
M40557-01CGRP II, rat (TFA)
MBS5817641alpha-CGRP, rat TFA
M29899-01CGRP (83-119), rat TFA
MBS5817935Calcitonin Gene Related Peptide (CGRP) II, rat TFA
M38004-01Α-CGRP (mouse, rat)
H-2265.0500a-CGRP (mouse, rat)

Popular Products