NBI-27914

CAT: 0804-HY-135542-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-135542-01Size:5 mg
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Description
NBI-27914 is a potent and selective antagonist of CRFR1. The CRF receptors, CRFR1 and CRFR2, are members of the G protein-coupled receptor superfamily[1].
CAS Number
[184241-44-9]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nbi-27914.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=C(NC2=C(Cl)C(N(CC3CC3)CCC)=NC(C)=N2)C(Cl)=CC(Cl)=C1
Molecular Formula
C18H20Cl4N4
Molecular Weight
434.19
Precautions
H315, H319, H335
References & Citations
[1]Liaw CW, et al. Localization of agonist- and antagonist-binding domains of human corticotropin-releasing factor receptors. Mol Endocrinol. 1997;11 (13) :2048-2053.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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