Apoptosis inducer 22

• Description :

  Apoptosis inducer 22 (QR-5) is an apoptosis inducer with IC50 values ​​of 63.1 and 46.5 μM for colon cancer cell lines SW480 and HT29, respectively. Apoptosis inducer 22 induces apoptosis by inhibiting the Wnt/β-catenin axis in colon cancer cells. Apoptosis inducer 22 can be used in anti-colon cancer research.

• UNSPSC :

  12352005

• Target :

  Apoptosis; Wnt

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/apoptosis-inducer-22.html

• Smiles :

  FC(F)(F)C1(CC1)C2=CC(NC(NC3=CC=CC(OC)=C3)=O)=NO2

• Molecular Formula :

  C15H14F3N3O3

• Molecular Weight :

  341.29

• References & Citations :

  [1]Suresh, et al. "Isoxazolyl-urea derivative evokes apoptosis and paraptosis by abrogating the Wnt/β-catenin axis in colon cancer cells." Chemico-Biological Interactions 399 (2024) : 111143.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported