EB-0176

CAT: 0804-HY-145275-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-145275-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EB-0176 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.6439 and 0.0011 μM, respectively. EB-0176 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0176 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses[1].
CAS Number
[2758314-64-4]
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/eb-0176.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H]([C@@H]([C@](O)(C[C@@H]1NCCCCCCNC2=C(C=C(C=C2)C3=NC=CC=N3)[N+]([O-])=O)CO)O)O
Molecular Formula
C23H33N5O7
Molecular Weight
491.54
References & Citations
[1]Karade SS, et al. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. J Med Chem. 2021;64 (24) :18010-18024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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