DOTA-PSMA-EB-01

CAT: 0804-HY-158266-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-158266-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

DOTA-PSMA-EB-01 (Compound LNC1003) is a specific inhibitor of PSMA (IC50= 10.77 nM) .DOTA-PSMA-EB-01 enhances the uptake and retention time of 177Lu in tumors[1]. DOTA-PSMA-EB-01 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

Product Name Alternative

LNC1003

UNSPSC

12352209

Target

PSMA; Radionuclide-Drug Conjugates (RDCs)

Type

Peptides

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dota-psma-eb-01.html

Purity

97.02

Solubility

DMSO : 6.67 mg/mL (ultrasonic)

Smiles

CC1=C(C=CC(C2=CC(C)=C(C=C2)NC([C@@H](NC(CN3CCN(CCN(CCN(CC3)CC(O)=O)CC(O)=O)CC(O)=O)=O)CCCCNC(CCOCCOCCC(NC[C@H]4CC[C@@H](CC4)C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC5=CC=C6C=CC=CC6=C5)=O)=O)=O)=O)=C1)/N=N/C7=C(C8=C(C(S(=O)(O)=O)=CC(S(=O)(O)=O)=C8N)C=C7)O

Molecular Formula

C87H115N15O28S2

Molecular Weight

1883.06

References & Citations

[1]Wen X, et al. Development of [177Lu]Lu-LNC1003 for radioligand therapy of prostate cancer with a moderate level of PSMA expression. Eur J Nucl Med Mol Imaging. 2023 Jul;50 (9) :2846-2860.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

RDC Peptide

Related Products

Catalog	Name
HY-P10741-01	DOTA-EB-TATE
HY-173116	DOTA-XYIMSR-01
HY-163683-01	EB-PSMA-617
HY-175612	DOTA-ALB-01
HY-163040	DOTA-Tyr-Lys-DOTA
HY-P11254	DOTA-FAPT
HY-163039	DOTA-biotin
HY-139564	DOTA Zoledronate
HY-W802013	DOTA-4AMP
HY-W038001	DOTA-benzene

Alternative Products

Catalog	Name
TP3571-01	DOTA-PSMA-EB-01
TP2996-01	DOTA-EB-TATE
GTR19264979-01	DOTA-ALB-01
T206524-01	DOTA-XYIMSR-01
T88040-01	EB-PSMA-617
GTR19150528-01	JR11-PEG3-DOTA-PSMA-03
GTR19267069-01	DOTA-Tyr-Lys-DOTA
TRC-D535500-250MG	DOTA
BA5818-1	DOTA-LM3
4029066.0250	DOTA (OtBu) ₃

DOTA-PSMA-EB-01

Related Products

Alternative Products

Popular Products