EB-TCIP

CAT: 0804-HY-173364-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-173364-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
EB-TCIP (BAK-04-212) is a bivalent molecule comprised of AP1867 (HY-114434) and BI-3812 (HY-111381) . EB-TCIP can form a reversible ternary complex between FKBPF36V and BCL6BTB. EB-TCIP recruits FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, leading to rapid expression of BCL6 target genes (eg: SOCS2 and CXCL11) . EWS/FLI1 is a fusion transcription factors in Ewing sarcoma. EB-TCIP can be used for research of deregulated transcription in cancer[1].
Product Name Alternative
BAK-04-212
UNSPSC
12352005
Target
BCL6
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C(OC)C(OC)=CC([C@@H](C(N2CCCC[C@H]2C(O[C@@H](C3=CC=CC=C3OCC(NCCCCCCNC(C4CCN(C5=NC(NC6=CC(C=C(OCC(NC)=O)C(N7C)=O)=C7C(OC)=C6)=C(Cl)C=N5)CC4)=O)=O)CCC8=CC=C(OC)C(OC)=C8)=O)=O)CC)=C1
Molecular Formula
C68H86ClN9O15
Molecular Weight
1304.91
References & Citations
[1]Bond MJ, et al. Rewiring the fusion oncoprotein EWS/FLI1 in Ewing sarcoma with bivalent small molecules. bioRxiv [Preprint]. 2025 Mar 17:2025.03.14.643353.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-156531TCIP 1
HY-115463-01EB-3D
HY-145274EB-0156
HY-145273EB-0150
HY-142647-01EB-42486
HY-145275-01EB-0176
HY-15046EB-47
HY-108631-01EB-47 (dihydrochloride)
HY-163683-01EB-PSMA-617
HY-P10741-01DOTA-EB-TATE

Alternative Products

CatalogName
T206944-01EB-TCIP
MBS5821462TCIP 1
9026005EB
MBS3602841-01EB-3D
E37F035-50-testsEB Eraser
ABC-TC0233EB-3
A4528-50EB 47
BA3689-1EB-42486
M26189-01EB-47
T62793-01EB-0150

Popular Products