Ezetimibe phenoxy glucuronide-d4

CAT: 0804-HY-135391SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-135391SSize:1 mg
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Description
Ezetimibe phenoxy glucuronide-d4 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].
CAS Number
[1426174-41-5]
Product Name Alternative
Ezetimibe glucuronide-d4; Ezetimibe β-D-glucuronide-d4
UNSPSC
12352005
Target
Drug Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
89.34
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=CC=C([C@H]([C@H]3CC[C@@H](C4=CC=C(F)C=C4)O)N(C5=C([2H])C([2H])=C(F)C([2H])=C5[2H])C3=O)C=C2
Molecular Formula
C30H25D4F2NO9
Molecular Weight
589.57
References & Citations
[1]Stolk MF, et al. Severe hepatic side effects of ezetimibe. Clin Gastroenterol Hepatol. 2006 Jul;4 (7) :908-11.|[2]Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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Alternative Products

CatalogName
MF-0022275-01Ezetimibe phenoxy glucuronide-D4
RM-E262035-01Ezetimibe Phenoxy Glucuronide
MBS6035745-01Ezetimibe b-D-Glucuronide (Ezetimibe Phenoxy Glucuronide)
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TRC-E975030-10MGEzetimibe Phenoxy Beta-D-Glucuronide
011907Ezetimibe-d4 β-D-Glucuronide
RM-E262164-01Ezetimibe-D4 Phenolic Glucuronide
RM-E262166-01Ezetimibe-D4 Hydroxy Glucuronide
293359-01Ezetimibe-D-glucuronide D4
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