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Ezetimibe hydroxy glucuronide

CAT: 0804-HY-135245-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-135245-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe.
CAS Number
536709-33-8
Product Name Alternative
SCH 488128; Ezetimibe hydroxy β-D-Glucuronide
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ezetimibe-hydroxy-glucuronide.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1O[C@H](C2=CC=C(F)C=C2)CC[C@@H]3[C@@H](C4=CC=C(O)C=C4)N(C5=CC=C(F)C=C5)C3=O
Molecular Formula
C30H29F2NO9
Molecular Weight
585.55
Precautions
H302, H315, H319, H335
References & Citations
[1]Anima Ghosal, et al. Identification of human UDP-glucuronosyltransferase enzyme (s) responsible for the glucuronidation of ezetimibe (Zetia) . Drug Metab Dispos. 2004 Mar;32 (3) :314-20.|[2]Ghosal A, et al. Identification of human UDP-glucuronosyltransferase enzyme (s) responsible for the glucuronidation of ezetimibe (Zetia) . Drug Metab Dispos. 2004 Mar;32 (3) :314-20.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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