PLP (180-199) (TFA)

• UNSPSC Description:

  PLP (180-199) TFA is the TFA salt form of PLP (180-199) (HY-P5462). PLP (180-199) TFA induces the activation and differentiation of T cells, and induces the experimental autoimmune encephalomyelitis (EAE) in mouse model[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/plp-180-199-tfa.html

• Purity:

  99.21

• Solubility:

  H2O : 12 mg/mL (ultrasonic;warming)

• Smiles:

  O=C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CO)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CC=CC=C2)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@H](CS)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@@H](N)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F.[x]

• Molecular Weight:

  2085.34 (free base)

• References & Citations:

  [1]Lyons JA, et al., B cells limit epitope spreading and reduce severity of EAE induced with PLP peptide in BALB/c mice. J Autoimmun. 2008 Sep;31(2):149-55.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported