ATX-0126

CAT: 0804-HY-149167-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-149167-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATX-0126 (ATX 100) is an ionizable lipid based on thiocarbamate. ATX-0126 can be involved in the formation of lipid nanoparticles and is used in research such as nucleic acid delivery[1][2].
CAS Number
[2230647-37-5]
Product Name Alternative
ATX 100
UNSPSC
12352211
Hazard Statement
H302, H315, H319
Target
Biochemical Assay Reagents; Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mrna-encapsulating-lipid-excipient-1.html
Purity
99.94
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 20 mg/mL (ultrasonic)
Smiles
O=C(N(CCCC(OC(CCCCCCC)CCCCCCC)=O)CCCC(OC(CCCCCCC)CCCCCCC)=O)SCCCN(C)C
Molecular Formula
C44H86N2O5S
Molecular Weight
755.23
Precautions
H302, H315, H319
References & Citations
[1]Kumar Rajappan, et al. Development of a Safe and Scalable Process for the Production of a High-Purity Thiocarbamate-Based Ionizable Lipid as an Excipient in mRNA-Encapsulating Lipid Nanoparticles. Org. Process Res. Dev. 2021, 25, 6, 1383-1390.|[2]Preparation of ionizable cationic lipids for RNA delivery. US20180170866A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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