ATX-0126

• UNSPSC Description:

  ATX-0126 (Compound 2) is a Thiocarbamate-Based Ionizable Lipid. ATX-0126 can be used as an excipient in mRNA-encapsulating lipid nanoparticle[1].

• Target Antigen:

  Biochemical Assay Reagents; Liposome

• Type:

  Oligonucleotides

• Related Pathways:

  Metabolic Enzyme/Protease;Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/mrna-encapsulating-lipid-excipient-1.html

• Solubility:

  DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)|Ethanol : 20 mg/mL (ultrasonic)

• Smiles:

  O=C(N(CCCC(OC(CCCCCCC)CCCCCCC)=O)CCCC(OC(CCCCCCC)CCCCCCC)=O)SCCCN(C)C

• Molecular Weight:

  755.23

• References & Citations:

  [1]Kumar Rajappan, et al. Development of a Safe and Scalable Process for the Production of a High-Purity Thiocarbamate-Based Ionizable Lipid as an Excipient in mRNA-Encapsulating Lipid Nanoparticles. Org. Process Res. Dev. 2021, 25, 6, 1383-1390.|[2]Preparation of ionizable cationic lipids for RNA delivery. US20180170866A1

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2230647-37-5