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ATX-IN-1

CAT: 0931-T205718-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205718-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PDE
Related Pathways
Metabolism
Bioactivity
ATX-IN-1 (compound 35) is an ATX inhibitor with an IC50 of 0.7 nM, demonstrating anti-inflammatory properties. It effectively suppresses the TGF-β/Smad pathway and reduces collagen deposition, alleviating fibrosis in a Bleomycin-induced mouse model. This compound also exhibits good oral bioavailability (F=69.5%) and microsomal stability.
Molecular Formula
C25H22N6O5
Molecular Weight
486.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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