PI3Kα-IN-9
CAT:
804-HY-150618-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PI3Kα-IN-9
- CAS Number: 2715287-67-3
- UNSPSC Description: PI3Kα-IN-9 (compound 27) is a selective, long-acting and oral active PI3Kα inhibitor with IC50 values of 4.4, 128, 146 and 153 nM for PI3Kα, PI3Kγ, PI3Kδ and PI3Kβ, respectively. PI3Kα-IN-9 has antiproliferative activity and induces apoptosis. PI3Kα-IN-9 can be used for cancer research[1].
- Target Antigen: Apoptosis; PI3K
- Type: Reference compound
- Related Pathways: Apoptosis;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pi3kα-in-9.html
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
- Smiles: NC1=NC2=CC(C3=NC(N4CCOCC4)=NC(N5CCOCC5)=N3)=CC=C2O1
- Molecular Weight: 383.40
- References & Citations: [1]Hou Y, et, al. Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer. J Med Chem. 2022 Jul 14.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported