PI3Kα-IN-19

PI3Kα-IN-19

• CAS Number: 885692-56-8
• UNSPSC Description: PI3Kα-IN-19 (Compound 1) is a PI3Kα inhibitor with a targeted binding site at the p110α catalytic subunit. PI3Kα is one of the most common dysregulated kinases used in cancer research[1].
• Target Antigen: PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3kα-in-19.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=NC(C#N)=CN1)NC2=CC=C(C(CC3)CCN3C(C4=C[N+]([O-])=CC=C4)=O)C=C2C5=CCCCC5
• Molecular Weight: 496.56
• References & Citations: [1]Shafiq, Muhammad et al. “A deep learning-based theoretical protocol to identify potentially isoform-selective PI3Kα inhibitors.” Molecular diversity, 10.1007/s11030-023-10799-0. 2 Feb. 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported