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DHX9-IN-3

CAT: 0804-HY-160007-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160007-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DHX9-IN-3 (Compound 621) is an inhibitor of ATP-dependent RNA helicase A (DHX9) . DHX9-IN-3 has an IC50 of 8.7 nM for anti-proliferation in LS411N cells. DHX9-IN-3 can be used in the study of cancer[1].
CAS Number
2973401-57-7
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-3.html
Purity
99.78
Solubility
DMSO : 28.57 mg/mL (ultrasonic; adjust pH to 5 with 1 M HCl)
Smiles
O=C(C1=CC(C2=NC=CC=C2OCC3=CC(F)=CN=C3)=C(C)S1)NC4=CC(Cl)=CC(NS(=O)(C)=O)=C4
Molecular Formula
C24H20ClFN4O4S2
Molecular Weight
547.02
References & Citations
[1]Matthew H, et al. Inhibitors of rna helicase dhx9 and uses thereof. WO2023154519A1. 2023-08-17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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