Products for Research Use Only
RegisterLogin

DHX9-IN-6

CAT: 0804-HY-160010-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-160010-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DHX9-IN-6 (Compound 620) is an ATP-dependent inhibitor of RNA helicase A (DHX9) with potential for cancer research[1].
CAS Number
2973401-56-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhx9-in-6.html
Purity
98.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=C(OCC3=CC(F)=CN=C3)C=CC=N2)=CS1)NC4=CC(Cl)=CC(NS(=O)(C)=O)=C4
Molecular Formula
C23H18ClFN4O4S2
Molecular Weight
532.99
References & Citations
[1]DANIELS Matthew H., et al. Preparation of imidazopyridines, thienopyrimidines, pyrrolopyrimidines and related heterocycles as inhibitors of RNA helicase DHX9 useful in treatment of cancers. World Intellectual Property Organization, WO2023154519 A1 2023-08-17
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Dhx9-IN-6
CAS Number2973401-56-6
PubChem CID169145026
IUPAC NameN-[3-chloro-5-(methanesulfonamido)phenyl]-4-[3-[(5-fluoro-3-pyridinyl)methoxy]-2-pyridinyl]thiophene-2-carboxamide
Molecular FormulaC23H18ClFN4O4S2
Molecular Weight533.0
XLogP3.5
Topological Polar Surface Area147
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count8
Heavy Atom Count35
Formal Charge0
Complexity820
SMILES
CS(=O)(=O)NC1=CC(=CC(=C1)NC(=O)C2=CC(=CS2)C3=C(C=CC=N3)OCC4=CC(=CN=C4)F)Cl
InChI
InChI=1S/C23H18ClFN4O4S2/c1-35(31,32)29-19-8-16(24)7-18(9-19)28-23(30)21-6-15(13-34-21)22-20(3-2-4-27-22)33-12-14-5-17(25)11-26-10-14/h2-11,13,29H,12H2,1H3,(H,28,30)
InChIKey
NPHAXUSEUGJGNE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Dhx9-IN-6
CAS: 2973401-56-6
CID: 169145026
Formula: C23H18ClFN4O4S2
MW: 533.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight533.0
XLogP33.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count8
Exact Mass532.0442033
Monoisotopic Mass532.0442033
Topological Polar Surface Area147 Ų
Heavy Atom Count35
Formal Charge0
Complexity820
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-157607DHX9-IN-15
HY-157605DHX9-IN-11
HY-170684DHX9-IN-19
HY-157609DHX9-IN-12
HY-157606DHX9-IN-13
HY-160813DHX9-IN-18
HY-157612DHX9-IN-16
HY-157611DHX9-IN-17
HY-160008-01DHX9-IN-4
HY-160009-01DHX9-IN-5

Alternative Products

CatalogName
T86202-01DHX9-IN-6
522264-01DHX9
YP-W10065-01Human DHX9 (DHX9) ELISA Kit
70R-16833DHX9 antibody
T86198-01DHX9-IN-17
T86192-01DHX9-IN-11
T86191-01DHX9-IN-10
DF12266-BPDHX9 Peptide
BUP01568-01DHX9-IN-2
BUP20299-01DHX9-IN-4

Popular Products