AF488 DBCO

AF488 DBCO

• UNSPSC Description: AF488 DBCO is a fluorescent dye that labels azide-containing biomolecules. DBCO is the bioorthogonal partner of azide that allows covalent coupling in the absence of copper. AF488 is a bright, photostable green fluorophore. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively[1][2].
• Target Antigen: Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/af488-dbco.html
• Solubility: DMSO : 4.68 mg/mL (ultrasonic;warming)
• Smiles: O=C(O)C1=C(C=CC(C(NCCCCCC(N2CC3=C(C#CC4=C2C=CC=C4)C=CC=C3)=O)=O)=C1)C5=C(C6=[O+]C7=C5C=CC(N)=C7S(=O)([O-])=O)C=CC(N)=C6S(=O)(O)=O.CCN(CC)CC
• Molecular Weight: 936.06
• References & Citations: [1]Elena Boero, et al. Purified complement C3b triggers phagocytosis and activation of human neutrophils via complement receptor 1. Sci Rep. 2023 Jan 6;13(1):274.|[2]Chakraborty S, Hu S Y, Wu S H, et al. The interaction affinity between vascular cell adhesion molecule-1 (VCAM-1) and very late antigen-4 (VLA-4) analyzed by quantitative FRET[J]. PLoS One, 2015, 10(3): e0121399.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported