BG-DBCO

• Description :

  BG-DBCO is a DBCO-conjugated Benzylguanine. BG-DBCO, SNAP-E3 fusion protein and Ligand-N3 form a protein complex. BG-DBCO is conjugated with JQ1-N3-C10 to obtain BG-JQ1. BG-JQ1, administered together with SIAH1-SN mRNA, effectively inhibits the growth of small cell carcinoma of the adrenocortical gland[1].

• Product Name Alternative :

  SNAP-DBCO

• UNSPSC :

  12352005

• Target :

  Drug Derivative; Drug Intermediate

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  NC1=NC2=C(C(OCC3=CC=C(C=C3)CNC(CCC(N4CC5=C(C#CC6=CC=CC=C46)C=CC=C5)=O)=O)=N1)N=CN2

• Molecular Formula :

  C32H27N7O3

• Molecular Weight :

  557.60

• References & Citations :

  [1]Teng X, et al. ClickRNA-PROTAC for Tumor-Selective Protein Degradation and Targeted Cancer Therapy. J Am Chem Soc. 2024 Oct 9;146 (40) :27382-27391.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [1820756-74-8]