DBCO-PEG2-DBCO

• Description:

  DBCO-PEG2-DBCO is a click chemistry reagent containing a DBCO group. DBCO-PEG2-DBCO is a PEG linker containing two terminal DBCO groups. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. T Reagent grade, for research use only[1].

• UNSPSC:

  12352005

• Target:

  ADC Linker

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dbco-peg2-dbco.html

• Purity:

  95.43

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)NCCOCCOCCNC(CCC(N4C5=C(C#CC6=C(C4)C=CC=C6)C=CC=C5)=O)=O

• Molecular Formula:

  C44H42N4O6

• Molecular Weight:

  722.83

• References & Citations:

  [1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14 (8) :779-789.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2639395-48-3]