Products for Research Use Only
RegisterLogin

Taltobulin intermediate-4

CAT: 0804-HY-41055-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-41055-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Taltobulin intermediate-4 is an intermediate in the synthesis of Taltobulin. Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
CAS Number
187345-37-5
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/taltobulin-intermediate-4.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)[C@@H](/C=C(C)/C(OCC)=O)N(C([C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)C
Molecular Formula
C22H40N2O5
Molecular Weight
412.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63 (8) :1838-45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-41054-01Taltobulin intermediate-3
HY-41047-01Taltobulin intermediate-1
HY-41066Taltobulin intermediate-5
HY-46004Taltobulin intermediate-10
HY-41043-01Taltobulin intermediate-2
HY-46005Taltobulin intermediate-11
HY-46006Taltobulin intermediate-12
HY-41070-01Taltobulin intermediate-8
HY-41069-01Taltobulin intermediate-7
HY-41067-01Taltobulin intermediate-6

Alternative Products

CatalogName
OR1034542-01Taltobulin intermediate-4
OR1032645-01Taltobulin intermediate-1
T208349-01Taltobulin intermediate-7
GTR19261385-01Taltobulin intermediate-6
T208431-01Taltobulin intermediate-12
OR1006062Taltobulin intermediate-2
GTR19261384-01(6R) -Taltobulin intermediate-9
BA2326-10Taltobulin
T75240-01Taltobulin hydrochloride
A21264-50Taltobulin 50mg

Popular Products