BVT-3498

• Description:

  BVT-3498 (AMG-311) is an inhibitor for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) [1].

• Product Name Alternative:

  AMG-311

• UNSPSC:

  12352005

• Target:

  11β-HSD

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/bvt-3498.html

• Smiles:

  ClC1=C(C)C(S(NC2=NC(CCN3CCOCC3=O)=CS2)(=O)=O)=CC=C1

• Molecular Formula:

  C16H18ClN3O4S2

• Molecular Weight:

  415.91

• References & Citations:

  [1]Venier O, et al., Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D. Bioorg Med Chem Lett. 2013 Apr 15;23 (8) :2414-21.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [376641-49-5]