NITD-349

• Description:

  NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv.

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/NITD-349.html

• Purity:

  98.98

• Solubility:

  DMSO : ≥ 310 mg/mL

• Smiles:

  O=C(C(N1)=CC2=C1C=C(F)C=C2F)NC3CCC(C)(C)CC3

• Molecular Formula:

  C17H20F2N2O

• Molecular Weight:

  306.35

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Rao SP, et al. Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis. Sci Transl Med. 2013 Dec 4;5 (214) :214ra168.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1473450-62-2]