NITD-349

• Description :

  NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/NITD-349.html

• Purity :

  98.98

• Solubility :

  DMSO : ≥ 310 mg/mL

• Smiles :

  O=C(C(N1)=CC2=C1C=C(F)C=C2F)NC3CCC(C)(C)CC3

• Molecular Formula :

  C17H20F2N2O

• Molecular Weight :

  306.35

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Rao SP, et al. Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis. Sci Transl Med. 2013 Dec 4;5 (214) :214ra168.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1473450-62-2]