Products for Research Use Only
RegisterLogin

DBCO-PEG4-VA-PBD

CAT: 0804-HY-133433-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-133433-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1]. DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
CAS Number
2241644-09-5
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-peg4-va-pbd.html
Purity
99.68
Solubility
DMSO : ≥ 100 mg/mL
Smiles
[H][C@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCC(N9C%10=CC=CC=C%10C#CC%11=CC=CC=C%11C9)=O)=O)=O)=O)=O)C=C8)C1
Molecular Formula
C80H87N9O16
Molecular Weight
1430.60
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, stored under nitrogen
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents

Related Products

CatalogName
HY-126685-01Mal-PEG4-VA-PBD
HY-176765-01DBCO-PEG4-VA-PABC-MMAE
HY-130346-01DBCO-PEG4-DBCO
HY-126669Mal-PEG4-VA
HY-120770-01DBCO-PEG4-Maleimide
HY-136049APN-PEG4-DBCO
HY-133430DBCO-PEG4-alkyne
HY-133492-01DBCO-PEG4-MMAF
HY-140308-01DBCO-PEG4-triethoxysilane
HY-130435-01DBCO-PEG4-amine

Alternative Products

CatalogName
GTR19225671-01DBCO-PEG4-VA-PBD
T18289-01Mal-PEG4-VA-PBD
GTR19263955-01DBCO-PEG4-VA-PABC-MMAE
MBS5768950DBCO-PEG4-DBCO
GTR19225339-01Mal-PEG4-VA
GTR19226746-01DBCO-PEG4-amine
BA2690-1DBCO-PEG4-MMAF
RGC71160-01DBCO-PEG4-alcohol
HGD78837-01DBCO-PEG4-desthiobiotin
CLK-033-SDBCO-PEG4-FLAG

Popular Products