APN-PEG4-DBCO

CAT: 0804-HY-136049Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-136049Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
APN-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. APN-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apn-peg4-dbco.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC(NCCOCCOCCOCCOCCC(NC1=CC=C(C#CC#N)C=C1)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
Molecular Formula
C39H40N4O7
Molecular Weight
676.76
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker

Related Products

CatalogName
HY-130346-01DBCO-PEG4-DBCO
HY-136030APN-PEG4-PFP
HY-136044APN-PEG4-BCN
HY-136045APN-PEG4-tetrazine
HY-180568Bromoacetamide-PEG4-DBCO
HY-133492-01DBCO-PEG4-MMAF
HY-120770-01DBCO-PEG4-Maleimide
HY-133430DBCO-PEG4-alkyne
HY-130435-01DBCO-PEG4-amine
HY-140308-01DBCO-PEG4-triethoxysilane

Alternative Products

CatalogName
MBS5770325APN-PEG4-DBCO
MBS5768950DBCO-PEG4-DBCO
MF-0006264-01APN-PEG4-BCN
MF-0034477-01APN-PEG4-tetrazine
MBS5770326APN-PEG4-PFP
M33334-01DBCO-PEG4-Biotin
M11044-01DBCO-PEG4 amine
JH917403DBCO-PEG4-Acid
abx085507-01DBCO-PEG4-NH2
MD048025-4-01DBCO-PEG4-SPA

Popular Products