Products for Research Use Only
RegisterLogin

DBCO-PEG4-VA-PABC-MMAE

CAT: 0804-HY-176765-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-176765-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DBCO-PEG4-VA-PABC-MMAE is a drug-linker conjugate for ADC. DBCO-PEG4-VA-PABC-MMAE consists of a tubulin inhibitor (MMAE) and a cleavable linker (DBCO-PEG4-VA-PABC). DBCO-PEG4-VA-PABC-MMAE can be used for synthesis of ADC ABBV-400 (HY-171945).
CAS Number
3049211-57-3
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.94
Smiles
O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C85H122N10O18
Molecular Weight
1571.93
References & Citations
[1]Hartley O, et al. Variant ligand conjugates for payload delivery. WO2024146707A1. 2024-07-11.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported

Related Products

CatalogName
HY-147239-01MC-VA-PABC-MMAE
HY-133433-01DBCO-PEG4-VA-PBD
HY-136314-01DBCO-PEG4-VC-PAB-MMAE
HY-176807DBCO-HS-PEG2-VA-PABC-SG3199
HY-164309DBCO-PEG3-Glu-Val-Cit-PABC-MMAE
HY-133492-01DBCO-PEG4-MMAF
HY-130346-01DBCO-PEG4-DBCO
HY-131158-01DBCO-PEG3-Glu-VC-PABC-MMAF
HY-177683N- (DBCO-PEG4) -N- (PEG4-Val-Cit-PAB-MMAE) -N- (PEG4-Val-Cit-PAB-Exatecan)
HY-126669Mal-PEG4-VA

Alternative Products

CatalogName
GTR19263955-01DBCO-PEG4-VA-PABC-MMAE
BA2641-1MC-VA-PABC-MMAE
BA2649-1DBCO-PEG4-VA-PBD
TRC-D489640-10MGDBCO-PEG4-PAB-MMAE
GTR19264634-01DBCO-HS-PEG2-VA-PABC-SG3199
BA2630-1DBCO-PEG4-VC-PAB-MMAE
T89265-01DBCO-PEG3-Glu-Val-Cit-PABC-MMAE
TRC-D489660-10MGDBCO-PEG4-Val-Cit-PAB-MMAE
MBS5768950DBCO-PEG4-DBCO

Popular Products