Mito-apocynin (C2)

• Description:

  Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP) -based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect[1].

• UNSPSC:

  12352005

• Target:

  Mitochondrial Metabolism

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mito-apocynin-c2.html

• Purity:

  98.38

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (NCC[P+] (C1=CC=CC=C1) (C2=CC=CC=C2) C3=CC=CC=C3) C4=CC=C (O) C (OC) =C4.[Br-]

• Molecular Formula:

  C28H27BrNO3P

• Molecular Weight:

  536.40

• References & Citations:

  [1]Zielonka J, et al. Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications. Chem Rev. 2017 Aug 9;117 (15) :10043-10120.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1254044-41-1