Mito-DK

• Description:

  Mito-DK is a small-molecule fluorescent dye with the capability of crosstalk-free response to polarity and mtDNA as well as mitochondrial morphology. Mito-DK has high photostability, low cytotoxicity, and good mitochondria-targeting properties. Mito-DK can be used for real-time tracking and multidimensional assessing of mitochondria-related pyroptosis in cancer cells[1].

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye; Pyroptosis

• Type:

  Dye Reagents

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mito-dk.html

• Purity:

  95.05

• Solubility:

  10 mM in DMSO

• Smiles:

  CCN1C2=CC=C(/C=C/C3=CC=[N+](C)C4=C3C=CC=C4)C=C2C5=C1C=CC(C#CC6=CC=C(F)C=C6)=C5.[I-]

• Molecular Formula:

  C34H26FIN2

• Molecular Weight:

  608.49

• References & Citations:

  [1]Zhao W, et al. Visualized Tracking and Multidimensional Assessing of Mitochondria-Associated Pyroptosis in Cancer Cells by a Small-Molecule Fluorescent Probe. Anal Chem. 2024 Apr 23;96 (16) :6381-6389.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported