Apocynin-d3

• UNSPSC Description:

  Apocynin-d3 is the deuterium labeled Apocynin[1]. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM[2][3][4].

• Target Antigen:

  Apoptosis; Autophagy

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis;Autophagy

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Solubility:

  10 mM in DMSO

• Smiles:

  [2H]C([2H])([2H])OC1=CC(C(C)=O)=CC=C1O

• Molecular Weight:

  169.19

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102.|[3]Stefanska J, et al. Mediators Inflamm, 2008, 106507.|[4]Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol. 2011 Mar 181(5):636-48.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  80404-23-5