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TLR7 agonist 24

CAT: 0804-HY-162725Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162725Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLR7 agonist 24 (Compound 21) is an agonist for TLR7 with EC50 of 3.72 μM. TLR7 agonist 24 can be used as a vaccine adjuvant when combined with Aluminum Hydroxide , that enhances the immune response against SARS-CoV-2 and hepatitis B antigens[1].
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr7-agonist-24.html
Smiles
OC1=C(O)C=C(C(N(CC2=CC=C(CN)C=C2)C(CCCC)=N3)=C3C(N)=N4)C4=C1
Molecular Formula
C22H25N5O2
Molecular Weight
391.47
References & Citations
[1]Kumar K, et al. Modulation of the Adjuvant Potential of Imidazoquinoline-Based TLR7/8 Agonists via Alum Adsorption[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7

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