Permethrin (Standard)

• Description:

  Permethrin (Standard) is the analytical standard of Permethrin. This product is intended for research and analytical applications. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.

• Product Name Alternative:

  NRDC-143 (Standard)

• UNSPSC:

  12352005

• Target:

  Mitochondrial Metabolism; Parasite; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease; Others

• Field of Research:

  Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/permethrin-standard.html

• Smiles:

  O=C(C1C(C)(C)C1/C=C(Cl)\Cl)OCC2=CC=CC(OC3=CC=CC=C3)=C2

• Molecular Formula:

  C21H20Cl2O3

• Molecular Weight:

  391.29

• References & Citations:

  [1]Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416.|[2]Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12 (11) :e0006933.|[3]Shelley LK, et al. Immunotoxic and cytotoxic effects of atrazine, permethrin and piperonyl butoxide to rainbow trout following in vitro exposure[J]. Fish Shellfish Immunol. 2012 Aug;33 (2) :455-8.|[4]Gassner B, et al. The pyrethroids permethrin and cyhalothrin are potent inhibitors of the mitochondrial complex I[J]. Journal of Pharmacology and Experimental Therapeutics, 1997, 281 (2) : 855-860.|[5]Kakko I, et al. The synaptosomal membrane bound ATPase as a target for the neurotoxic effects of pyrethroids, permethrin and cypermethrin[J]. Chemosphere. 2003 May;51 (6) :475-80.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [52645-53-1]