Permethrin-d5

• Description :

  Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].

• Product Name Alternative :

  NRDC-143-d5

• UNSPSC :

  12352005

• Hazard Statement :

  H302+H332-H317-H410

• Target :

  Parasite

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Purity :

  99.21

• Solubility :

  10 mM in DMSO|DMSO : 50mg/mL (ultrasonic)

• Smiles :

  C(=C(Cl)Cl)C1C(C(OCC2=CC(OC3=C(C(=C(C(=C3[2H])[2H])[2H])[2H])[2H])=CC=C2)=O)C1(C)C

• Molecular Formula :

  C21H15D5Cl2O3

• Molecular Weight :

  396.32

• Precautions :

  P261-P264-P270-P271-P272-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P501

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416.|[3]Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12 (11) :e0006933.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1794760-19-2]