Permethrin-d9

• Description:

  Permethrin-d9 is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.

• Product Name Alternative:

  NRDC-143-d9

• UNSPSC:

  12352005

• Target:

  Isotope-Labeled Compounds; Parasite

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Infection

• Purity:

  98.20

• Solubility:

  10 mM in DMSO

• Smiles:

  Cl/C(Cl)=C\C1C(C1(C)C)C(OCC2=C([2H])C(OC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=C([2H])C([2H])=C2[2H])=O

• Molecular Formula:

  C21H11D9Cl2O3

• Molecular Weight:

  400.34

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416.|[3]Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12 (11) :e0006933.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported