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CRBN modulator-1

CAT: 0804-HY-138040-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-138040-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM[1].
CAS Number
2407829-65-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/crbn-modulator-1.html
Purity
98.00
Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=CC(O)=CC4=CC=CC1=C34)=O
Molecular Formula
C17H12N2O5
Molecular Weight
324.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Nathanael Gray, et al. New crbn modulators. WO2020006262A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

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