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Ginsenoside Rh4

CAT: 0804-HY-N0905-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0905-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ginsenoside Rh4 is a rare saponin obtained from Panax notoginseng. Ginsenoside Rh4 activates Bax, caspase 3, caspase 8, and caspase 9. Ginsenoside Rh4 also induces autophagy.
CAS Number
174721-08-5
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Autophagy; Bcl-2 Family; Caspase; Endogenous Metabolite
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Ginsenoside-Rh4.html
Purity
99.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@@H]3/C(C)=C/C/C=C(C)\C)C)O)([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])[C@H](C1)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)C
Molecular Formula
C36H60O8
Molecular Weight
620.86
Precautions
H302
References & Citations
[1]Wu Q, et al. Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells. Biochem Pharmacol. 2018 Feb;148:64-74.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Bax; Caspase 3; Caspase 8; Caspase 9

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